SB 258585 hydrochloride
CAS No. 1216468-02-8
SB 258585 hydrochloride ( SB258585 )
产品货号. M10810 CAS No. 1216468-02-8
SB-258585 is a potent, selective and orally active 5-HT6 receptor antagonist with Ki of 8.9 nM.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥7857 | 有现货 |
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50MG | ¥16038 | 有现货 |
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100MG | ¥20250 | 有现货 |
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200MG | 获取报价 | 有现货 |
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500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称SB 258585 hydrochloride
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述SB-258585 is a potent, selective and orally active 5-HT6 receptor antagonist with Ki of 8.9 nM.
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产品描述SB-258585 is a potent, selective and orally active 5-HT6 receptor antagonist with Ki of 8.9 nM, >160-fold selectivity over other 5-HT receptor subtypes; also is an inhibitor of HCV entry in liver-derived cell lines as well as primary hepatocytes, modulates localization of the coreceptor tight junction protein claudin-1 (CLDN1) in a 5-HT6-independent manner, induces intracellular accumulation of CLDN1.
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同义词SB258585
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通路Endocrinology/Hormones
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靶点5-HT Receptor
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受体5-HT Receptor
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研究领域——
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适应症——
化学信息
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CAS Number1216468-02-8
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分子量523.81
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分子式C18H23ClIN3O3S
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纯度>98% (HPLC)
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溶解度——
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SMILESCN1CCN(CC1)C2=C(C=CC(=C2)NS(=O)(=O)C3=CC=C(C=C3)I)OC.Cl
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化学全称4-Iodo-N-[4-methoxy-3-(4-methyl-1-piperazinyl)phenyl]benzenesulfonamide hydrochloride
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Hirst WD, et al. Br J Pharmacol. 2000 Aug;130(7):1597-605.
2. Riva L, et al. J Virol. 2018 Apr 27;92(10). pii: e01982-17.
2. Riva L, et al. J Virol. 2018 Apr 27;92(10). pii: e01982-17.
产品手册
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